College of Agricultural Sciences

A. K. Ehrlich, Pennington, J. M., Wang, X., Rohlman, D., Punj, S., Löhr, C. V., Newman, M. T., Kolluri, S., and Kerkvliet, N. I., “Activation of the Aryl Hydrocarbon Receptor by 10-Cl-BBQ Prevents Insulitis and Effector T Cell Development Independently of Foxp3+ Regulatory T Cells in Nonobese Diabetic Mice.”, J Immunol, vol. 196, no. 1, pp. 264-73, 2016.

A. K. Ehrlich, Pennington, J. M., Tilton, S., Wang, X., Marshall, N. B., Rohlman, D., Funatake, C., Punj, S., O'Donnell, E. F., Yu, Z., Kolluri, S., and Kerkvliet, N. I., “AhR activation increases IL-2 production by alloreactive CD4 T cells initiating the differentiation of mucosal-homing Tim3 Lag3 Tr1 cells.”, Eur J Immunol, vol. 47, no. 11, pp. 1989-2001, 2017.

S. Sengupta, Bisson, W. H., Mathew, L. K., Kolluri, S., and Tanguay, R. L., “Alternate glucocorticoid receptor ligand binding structures influence outcomes in an in vivo tissue regeneration model”, Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, vol. 156, no. 2, pp. 121 - 129, 2012.

D. C. Koch, Jang, H. S., O'Donnell, E. F., Punj, S., Kopparapu, P. R., Bisson, W. H., Kerkvliet, N. I., and Kolluri, S., “Anti-androgen flutamide suppresses hepatocellular carcinoma cell proliferation via the aryl hydrocarbon receptor mediated induction of transforming growth factor-β1.”, Oncogene, 2015.

E. F. O'Donnell, Saili, K. S., Koch, D. C., Kopparapu, P. R., Farrer, D., Bisson, W. H., Mathew, L. K., Sengupta, S., Kerkvliet, N. I., Tanguay, R. L., and Kolluri, S., “The Anti-Inflammatory Drug Leflunomide Is an Agonist of the Aryl Hydrocarbon Receptor”, PLoS ONE, vol. 5, no. 10, p. e13128, 2010.

E. F. O'Donnell, Saili, K. S., Koch, D. C., Kopparapu, P. R., Farrer, D., Bisson, W. H., Mathew, L. K., Sengupta, S., Kerkvliet, N. I., Tanguay, R. L., and Kolluri, S. Kumar, “The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor.”, PLoS One, vol. 5, no. 10, 2010.

M. I. Dawson, Hobbs, P. D., Peterson, V. J., Leid, M., Lange, C. W., Feng, K. - C., Chen, G. -quan, Gu, J., Li, H., Kolluri, S., and , “Apoptosis induction in cancer cells by a novel analogue of 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalenecarboxylic acid lacking retinoid receptor transcriptional activation activity”, Cancer research, vol. 61, pp. 4723–4730, 2001.

E. F. O'Donnell, Jang, H. Sang, Pearce, M. C., Kerkvliet, N. I., and Kolluri, S., “The aryl hydrocarbon receptor is required for induction of p21cip1/waf1 expression and growth inhibition by SU5416 in hepatoma cells.”, Oncotarget, vol. 8, no. 15, pp. 25211-25225, 2017.

E. F. O'Donnell, Kopparapu, P. Rao, Koch, D. C., Jang, H. Sang, Phillips, J. Lynne, Tanguay, R. L., Kerkvliet, N. I., and Kolluri, S. Kumar, “The aryl hydrocarbon receptor mediates leflunomide-induced growth inhibition of melanoma cells.”, PLoS One, vol. 7, no. 7, p. e40926, 2012.

E. F. ’ Donnell, Kopparapu, P. Rao, Koch, D. C., Jang, H. Sang, Phillips, J. Lynne, Tanguay, R. L., Kerkvliet, N. I., and Kolluri, S., “The Aryl Hydrocarbon Receptor Mediates Leflunomide-Induced Growth Inhibition of Melanoma Cells”, PLoS ONE, vol. 7, no. 7, p. e40926, 2012.

E. F. O'Donnell, Koch, D. C., Bisson, W. H., Jang, H. S., and Kolluri, S., “The aryl hydrocarbon receptor mediates raloxifene-induced apoptosis in estrogen receptor-negative hepatoma and breast cancer cells”, Cell death & disease, vol. 5, p. e1038, 2014.

S. Punj, Kopparapu, P., Jang, H. Sang, Phillips, J. Lynne, Pennington, J. M., Rohlman, D., O'Donnell, E. F., Iversen, P. L., Kolluri, S., and Kerkvliet, N. I., “Benzimidazoisoquinolines: a new class of rapidly metabolized aryl hydrocarbon receptor (AhR) ligands that induce AhR-dependent Tregs and prevent murine graft-versus-host disease.”, PLoS One, vol. 9, no. 2, p. e88726, 2014.

M. C. Pearce, Satterthwait, A. C., Zhang, X. -kun, and Kolluri, S. Kumar, “Cancer therapeutics based on BCL-2 functional conversion.”, Apoptosis, vol. 24, no. 1-2, pp. 1-2, 2019.

C. Weiß, Kolluri, S., Kiefer, F., and Göttlicher, M., “Complementation of Ah receptor deficiency in hepatoma cells: negative feedback regulation and cell cycle control by the Ah receptor”, Experimental cell research, vol. 226, pp. 154–163, 1996.

B. Lin, Kolluri, S., Lin, F., Liu, W., Han, Y. - H., Cao, X., Dawson, M. I., Reed, J. C., and Zhang, X. -kun, “Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3”, Cell, vol. 116, pp. 527–540, 2004.

H. Li, Kolluri, S., Gu, J., Dawson, M. I., Cao, X., Hobbs, P. D., Lin, B., Chen, G. -quen, Lu, J. -song, Lin, F., and , “Cytochrome c release and apoptosis induced by mitochondrial targeting of nuclear orphan receptor TR3”, Science, vol. 289, pp. 1159–1164, 2000.

C. N. Cavasotto, Liu, G., James, S. Y., Hobbs, P. D., Peterson, V. J., Bhattacharya, A. A., Kolluri, S., Zhang, X. -kun, Leid, M., Abagyan, R., Liddington, R. C., and Dawson, M. I., “Determinants of Retinoid X Receptor Transcriptional Antagonism”, Journal of Medicinal Chemistry, vol. 47, no. 18, pp. 4360 - 4372, 2004.

A. D. Benninghoff, Bisson, W. H., Koch, D. C., Ehresman, D. J., Kolluri, S., and Williams, D. E., “Estrogen-like activity of perfluoroalkyl acids in vivo and interaction with human and rainbow trout estrogen receptors in vitro”, Toxicological sciences, p. kfq379, 2010.

K. J. Smith, Murray, I. A., Tanos, R., Tellew, J., Boitano, A. E., Bisson, W. H., Kolluri, S., Cooke, M. P., and Perdew, G. H., “Identification of a high-affinity ligand that exhibits complete aryl hydrocarbon receptor antagonism”, Journal of Pharmacology and Experimental Therapeutics, vol. 338, pp. 318–327, 2011.

H. Jang, Pearce, M. C., O'Donnell, E. F., Nguyen, B., Truong, L., Mueller, M. J., Bisson, W. H., Kerkvliet, N. I., Tanguay, R. L., and Kolluri, S., “Identification of a Raloxifene Analog That Promotes AhR-Mediated Apoptosis in Cancer Cells”, Biology (Basel), vol. 6, no. 4, 2017.

H. Sang Jang, Pearce, M. C., O'Donnell, E. F., Nguyen, B. Duc, Truong, L., Mueller, M. J., Bisson, W. H., Kerkvliet, N. I., Tanguay, R. L., and Kolluri, S., “Identification of a Raloxifene Analog That Promotes AhR-Mediated Apoptosis in Cancer Cells.”, Biology (Basel), vol. 6, no. 4, 2017.

E. Morgan, Gamble, J. T., Pearce, M. C., Elson, D. J., Tanguay, R. L., Kolluri, S. Kumar, and Reich, Norbert O, “Improved in vivo targeting of BCL-2 phenotypic conversion through hollow gold nanoshell delivery.”, Apoptosis, 2019.

M. C. Pearce, Gamble, J. T., Kopparapu, P. R., O'Donnell, E. F., Mueller, M. J., Jang, H. Sang, Greenwood, J. A., Satterthwait, A. C., Tanguay, R. L., Zhang, X. -kun, and Kolluri, S., “Induction of apoptosis and suppression of tumor growth by Nur77-derived Bcl-2 converting peptide in chemoresistant lung cancer cells.”, Oncotarget, vol. 9, no. 40, pp. 26072-26085, 2018.

S. K. Gupta, Chadha, K., Harris, J. D., Yurewicz, E. C., Sacco, A. G., Kolluri, S., and Afzalpurka, A., “Mapping of epitopes on porcine zona pellucida-3 alpha by monoclonal antibodies inhibiting oocyte-sperm interaction.”, Biology of reproduction, vol. 55, pp. 410–415, 1996.

S. Kolluri, Bruey-Sedano, N., Cao, X., Lin, B., Lin, F., Han, Y. - H., Dawson, M. I., and Zhang, X. -kun, “Mitogenic effect of orphan receptor TR3 and its regulation by MEKK1 in lung cancer cells”, Molecular and cellular biology, vol. 23, pp. 8651–8667, 2003.