College of Agricultural Sciences

A. Carnero, Blanco-Aparicio, C., Kondoh, H., Lleonart, M. E., Martinez-Leal, J. Fernando, Mondello, C., A Scovassi, I., Bisson, W. H., Amedei, A., Roy, R., and Bisson, W. H., “Disruptive chemicals, senescence and immortality”, Carcinogenesis, vol. 36, pp. S19–S37, 2015.

A. Carnero, Blanco-Aparicio, C., Kondoh, H., Lleonart, M. E., Martinez-Leal, J. Fernando, Mondello, C., A Scovassi, I., Bisson, W. H., Amedei, A., Roy, R., and Bisson, W. H., “Disruptive chemicals, senescence and immortality”, Carcinogenesis, vol. 36, pp. S19–S37, 2015.

K. Badri Narayanan, Ali, M., Barclay, B. J., Cheng, Q. Shawn, D’Abronzo, L., Dornetshuber-Fleiss, R., Ghosh, P. M., Guzman, M. J. Gonzalez, Lee, T. - J., Leung, P. Sing, and Bisson, W. H., “Disruptive environmental chemicals and cellular mechanisms that confer resistance to cell death”, Carcinogenesis, vol. 36, pp. S89–S110, 2015.

P. A. Thompson, Khatami, M., Baglole, C. J., Sun, J., Harris, S. A., Moon, E. - Y., Al-Mulla, F., Al-Temaimi, R., Brown, D. G., Colacci, A. Maria, and Bisson, W. H., “Environmental immune disruptors, inflammation and cancer risk”, Carcinogenesis, vol. 36, pp. S232–S253, 2015.

J. Ochieng, Nangami, G. N., Ogunkua, O., Miousse, I. R., Koturbash, I., Odero-Marah, V., McCawley, L., Nangia-Makker, P., Ahmed, N., Luqmani, Y., and Bisson, W. H., “The impact of low-dose carcinogens and environmental disruptors on tissue invasion and metastasis”, Carcinogenesis, vol. 36, pp. S128–S159, 2015.

F. J. Gonzalez, Jiang, C., Bisson, W. H., and Patterson, A. D., “Inhibition of farnesoid X receptor signaling shows beneficial effects in human obesity”, Journal of hepatology, 2015.

C. Jiang, Xie, C., Lv, Y., Li, J., Krausz, K. W., Shi, J., Brocker, C. N., Desai, D., Amin, S. G., Bisson, W. H., Liu, Y., Gavrilova, O., Patterson, A. D., and Gonzalez, F. J., “Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction”, Nature Communications, vol. 6, p. 10166, 2015.

B. C. Goodale, La Du, J. K., Tilton, F., Sullivan, C. M., Bisson, W. H., Waters, K. M., and Tanguay, R. L., “Ligand-Specific Transcriptional Mechanisms Underlie Aryl Hydrocarbon Receptor-Mediated Developmental Toxicity of Oxygenated PAHs”, Toxicological Sciences, vol. 147, no. 2, pp. 397 - 411, 2015.

B. C. Goodale, La Du, J., Tilton, S. C., Sullivan, C. M., Bisson, W. H., Waters, K. M., and Tanguay, R. L., “Ligand-Specific Transcriptional Mechanisms Underlie Aryl Hydrocarbon Receptor-Mediated Developmental Toxicity of Oxygenated PAHs.”, Toxicol Sci, vol. 147, no. 2, pp. 397-411, 2015.

B. C. Goodale, La Du, J. K., Tilton, S. C., Sullivan, C. M., Bisson, W. H., Waters, K. M., and Tanguay, R., “Ligand-specific transcriptional mechanisms underlie aryl hydrocarbon receptor-mediated developmental toxicity of oxygenated PAHs”, Toxicological Sciences, p. kfv139, 2015.

R. Nahta, Al-Mulla, F., Al-Temaimi, R., Amedei, A., Andrade-Vieira, R., Bay, S., Brown, D. G., Calaf, G. M., Castellino, R. C., Cohen-Solal, K. A., and Bisson, W. H., “Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression”, Carcinogenesis, vol. 36, pp. S2–S18, 2015.

B. R Robey, Weisz, J., Kuemmerle, N., Salzberg, A. C., Berg, A., Brown, D. G., Kubik, L., Palorini, R., Al-Mulla, F., Al-Temaimi, R., and Bisson, W. H., “Metabolic reprogramming and dysregulated metabolism: cause, consequence and/or enabler of environmental carcinogenesis?”, Carcinogenesis, vol. 36, pp. S203–S231, 2015.

W. Engström, Darbre, P., Eriksson, S., Gulliver, L., Hultman, T., Karamouzis, M. V., Klaunig, J. E., Mehta, R., Moorwood, K., Sanderson, T., and Bisson, W. H., “The potential for chemical mixtures from the environment to enable the cancer hallmark of sustained proliferative signalling”, Carcinogenesis, vol. 36, pp. S38–S60, 2015.

E. F. O'Donnell, Koch, D. C., Bisson, W. H., Jang, H. S., and Kolluri, S., “The aryl hydrocarbon receptor mediates raloxifene-induced apoptosis in estrogen receptor-negative hepatoma and breast cancer cells”, Cell death & disease, vol. 5, p. e1038, 2014.

T. Wang, Bisson, W. H., Mäser, P., Scapozza, L., and Picard, D., “Differences in conformational dynamics between Plasmodium falciparum and human Hsp90 orthologues enable the structure-based discovery of pathogen-selective inhibitors”, Journal of medicinal chemistry, vol. 57, pp. 2524–2535, 2014.

Y. Kang, Nian, H., Rajendran, P., Kim, E., Dashwood, W. M., Pinto, J. T., Boardman, L. A., Thibodeau, S. N., Limburg, P. J., Löhr, C. V., and Bisson, W. H., “HDAC8 and STAT3 repress BMF gene activity in colon cancer cells”, Cell death & disease, vol. 5, p. e1476, 2014.

C. V. Gerlach, Das, S. R., Volz, D. C., Bisson, W. H., Kolluri, S., and Tanguay, R., “Mono-substituted isopropylated triaryl phosphate, a major component of Firemaster 550, is an AHR agonist that exhibits AHR-independent cardiotoxicity in zebrafish”, Aquatic Toxicology, vol. 154, pp. 71–79, 2014.

C. V. Gerlach, Das, S. R., Volz, D. C., Bisson, W. H., Kolluri, S., and Tanguay, R. L., “Mono-substituted isopropylated triaryl phosphate, a major component of Firemaster 550, is an AHR agonist that exhibits AHR-independent cardiotoxicity in zebrafish”, Aquatic Toxicology, vol. 154, pp. 71 - 79, 2014.

C. V. Gerlach, Das, S. R., Volz, D. C., Bisson, W. H., Kolluri, S. K., and Tanguay, R. L., “Mono-substituted isopropylated triaryl phosphate, a major component of Firemaster 550, is an AHR agonist that exhibits AHR-independent cardiotoxicity in zebrafish.”, Aquat Toxicol, vol. 154, pp. 71-9, 2014.

A. Perkins, Phillips, J. Lynne, Kerkvliet, N. I., Tanguay, R. L., Perdew, G. H., Kolluri, S. K., and Bisson, W. H., “A Structural Switch between Agonist and Antagonist Bound Conformations for a Ligand-Optimized Model of the Human Aryl Hydrocarbon Receptor Ligand Binding Domain.”, Biology (Basel), vol. 3, no. 4, pp. 645-69, 2014.

A. Perkins, Phillips, J. Lynne, Kerkvliet, N. I., Tanguay, R., Perdew, G. H., Kolluri, S., and Bisson, W. H., “A structural switch between agonist and antagonist bound conformations for a ligand-optimized model of the human aryl hydrocarbon receptor ligand binding domain”, Biology, vol. 3, pp. 645–669, 2014.

A. Perkins, Phillips, J. Lynne, Kerkvliet, N., Tanguay, R., Perdew, G., Kolluri, S., and Bisson, W. H., “A Structural Switch between Agonist and Antagonist Bound Conformations for a Ligand-Optimized Model of the Human Aryl Hydrocarbon Receptor Ligand Binding Domain”, Biology, vol. 399, no. 4, pp. 645 - 669, 2014.

S. Tardy, Orsato, A., Mologni, L., Bisson, W. H., Donadoni, C., Gambacorti-Passerini, C., Scapozza, L., Gueyrard, D., and Goekjian, P. G., “Synthesis and biological evaluation of benzo [4, 5] imidazo [1, 2-c] pyrimidine and benzo [4, 5] imidazo [1, 2-a] pyrazine derivatives as anaplastic lymphoma kinase inhibitors”, Bioorganic & medicinal chemistry, vol. 22, pp. 1303–1312, 2014.

M. Ceccon, Mologni, L., Bisson, W. H., Scapozza, L., and Gambacorti-Passerini, C., “Crizotinib-resistant NPM-ALK mutants confer differential sensitivity to unrelated Alk inhibitors”, Molecular Cancer Research, vol. 11, pp. 122–132, 2013.

P. Rajendran, Kidane, A. I., Yu, T. - W., Dashwood, W. - M., Bisson, W. H., Löhr, C. V., Ho, E., Williams, D. E., and Dashwood, R. H., “HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates”, Epigenetics, vol. 8, pp. 612–623, 2013.