Found 81 results
Author Title [ Type(Desc)] Year
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Journal Article
B. C. Goodale, La Du, J., Tilton, S. C., Sullivan, C. M., Bisson, W. H., Waters, K. M., and Tanguay, R. L., Ligand-Specific Transcriptional Mechanisms Underlie Aryl Hydrocarbon Receptor-Mediated Developmental Toxicity of Oxygenated PAHs., Toxicol Sci, vol. 147, no. 2, pp. 397-411, 2015.
B. C. Goodale, La Du, J. K., Tilton, F., Sullivan, C. M., Bisson, W. H., Waters, K. M., and Tanguay, R. L., Ligand-Specific Transcriptional Mechanisms Underlie Aryl Hydrocarbon Receptor-Mediated Developmental Toxicity of Oxygenated PAHs, Toxicological Sciences, vol. 147, no. 2, pp. 397 - 411, 2015.
M. F. Miller, Goodson, W. H., Manjili, M. H., Kleinstreuer, N., Bisson, W. H., and Lowe, L., Low-Dose Mixture Hypothesis of Carcinogenesis Workshop: Scientific Underpinnings and Research Recommendations., Environ Health Perspect, 2017.
A. Sehrawat, Gao, L., Wang, Y., Bankhead, A., McWeeney, S. K., King, C. J., Schwartzman, J., Urrutia, J., Bisson, W. H., Coleman, D. J., Joshi, S. K., Kim, D. - H., Sampson, D. A., Weinmann, S., Kallakury, B. V. S., Berry, D. L., Haque, R., Van Den Eeden, S. K., Sharma, S., Bearss, J., Beer, T. M., Thomas, G. V., Heiser, L. M., and Alumkal, J. J., LSD1 activates a lethal prostate cancer gene network independently of its demethylase function., Proc Natl Acad Sci U S A, 2018.
R. Nahta, Al-Mulla, F., Al-Temaimi, R., Amedei, A., Andrade-Vieira, R., Bay, S., Brown, D. G., Calaf, G. M., Castellino, R. C., Cohen-Solal, K. A., and Bisson, W. H., Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression, Carcinogenesis, vol. 36, pp. S2–S18, 2015.
A. C. Chlebowski, Garcia, G. R., La Du, J. K., Bisson, W. H., Truong, L., SL, M. Simonich, and Tanguay, R. L., Mechanistic investigations into the developmental toxicity of nitrated and heterocyclic PAHs., Toxicol Sci, 2017.
B. R Robey, Weisz, J., Kuemmerle, N., Salzberg, A. C., Berg, A., Brown, D. G., Kubik, L., Palorini, R., Al-Mulla, F., Al-Temaimi, R., and Bisson, W. H., Metabolic reprogramming and dysregulated metabolism: cause, consequence and/or enabler of environmental carcinogenesis?, Carcinogenesis, vol. 36, pp. S203–S231, 2015.
W. H. Bisson, Koch, D. C., O'Donnell, E. F., Khalil, S. M., Kerkvliet, N. I., Tanguay, R. L., Abagyan, R., and Kolluri, S. Kumar, Modeling of the aryl hydrocarbon receptor (AhR) ligand binding domain and its utility in virtual ligand screening to predict new AhR ligands, Journal of medicinal chemistry, vol. 52, pp. 5635–5641, 2009.
W. H. Bisson, Koch, D. C., Donnell, E. F. ’, Khalil, S. M., Kerkvliet, N. I., Tanguay, R. L., Abagyan, R., and Kolluri, S., Modeling of the Aryl Hydrocarbon Receptor (AhR) Ligand Binding Domain and Its Utility in Virtual Ligand Screening to Predict New AhR Ligands, Journal of Medicinal Chemistry, vol. 52, no. 18, pp. 5635 - 5641, 2009.
W. H. Bisson, Koch, D. C., O'Donnell, E. F., Khalil, S. M., Kerkvliet, N. I., Tanguay, R. L., Abagyan, R., and Kolluri, S. Kumar, Modeling of the aryl hydrocarbon receptor (AhR) ligand binding domain and its utility in virtual ligand screening to predict new AhR ligands., J Med Chem, vol. 52, no. 18, pp. 5635-41, 2009.
W. H. Bisson, Abagyan, R., and Cavasotto, C. N., Molecular basis of agonicity and antagonicity in the androgen receptor studied by molecular dynamics simulations, Journal of Molecular Graphics and Modelling, vol. 27, no. 4, pp. 452 - 458, 2008.
C. V. Gerlach, Das, S. R., Volz, D. C., Bisson, W. H., Kolluri, S., and Tanguay, R. L., Mono-substituted isopropylated triaryl phosphate, a major component of Firemaster 550, is an AHR agonist that exhibits AHR-independent cardiotoxicity in zebrafish, Aquatic Toxicology, vol. 154, pp. 71 - 79, 2014.
C. V. Gerlach, Das, S. R., Volz, D. C., Bisson, W. H., Kolluri, S. K., and Tanguay, R. L., Mono-substituted isopropylated triaryl phosphate, a major component of Firemaster 550, is an AHR agonist that exhibits AHR-independent cardiotoxicity in zebrafish., Aquat Toxicol, vol. 154, pp. 71-9, 2014.
C. V. Gerlach, Das, S. R., Volz, D. C., Bisson, W. H., Kolluri, S., and Tanguay, R., Mono-substituted isopropylated triaryl phosphate, a major component of Firemaster 550, is an AHR agonist that exhibits AHR-independent cardiotoxicity in zebrafish, Aquatic Toxicology, vol. 154, pp. 71–79, 2014.
M. J. Nemec, Kim, H., Marciante, A. B., Barnes, R. C., Hendrick, E. D., Bisson, W. H., Talcott, S. T., and Mertens-Talcott, S. U., Polyphenolics from mango (Mangifera indica L.) suppress breast cancer ductal carcinoma in situ proliferation through activation of AMPK pathway and suppression of mTOR in athymic nude mice., J Nutr Biochem, vol. 41, pp. 12-19, 2016.
W. Engström, Darbre, P., Eriksson, S., Gulliver, L., Hultman, T., Karamouzis, M. V., Klaunig, J. E., Mehta, R., Moorwood, K., Sanderson, T., and Bisson, W. H., The potential for chemical mixtures from the environment to enable the cancer hallmark of sustained proliferative signalling, Carcinogenesis, vol. 36, pp. S38–S60, 2015.
S. Raduner, Bisson, W. H., Abagyan, R., Altmann, K. - H., and Gertsch, J., Self-assembling cannabinomimetics: supramolecular structures of N-alkyl amides, Journal of natural products, vol. 70, pp. 1010–1015, 2007.
J. D. Chavez, Wu, J., Bisson, W. H., and Maier, C. S., Site-specific proteomic analysis of lipoxidation adducts in cardiac mitochondria reveals chemical diversity of 2-alkenal adduction, Journal of proteomics, vol. 74, pp. 2417–2429, 2011.
A. Dehner, Planker, E., Gemmecker, G., Broxterman, Q. B., Bisson, W. H., Formaggio, F., Crisma, M., Toniolo, C., and Kessler, H., Solution Structure, Dimerization, and Dynamics of a Lipophilic $\alpha$/310-Helical, C$\alpha$-Methylated Peptide. Implications for Folding of Membrane Proteins, Journal of the American Chemical Society, vol. 123, pp. 6678–6686, 2001.
A. Perkins, Phillips, J. Lynne, Kerkvliet, N. I., Tanguay, R. L., Perdew, G. H., Kolluri, S. K., and Bisson, W. H., A Structural Switch between Agonist and Antagonist Bound Conformations for a Ligand-Optimized Model of the Human Aryl Hydrocarbon Receptor Ligand Binding Domain., Biology (Basel), vol. 3, no. 4, pp. 645-69, 2014.
A. Perkins, Phillips, J. Lynne, Kerkvliet, N., Tanguay, R., Perdew, G., Kolluri, S., and Bisson, W. H., A Structural Switch between Agonist and Antagonist Bound Conformations for a Ligand-Optimized Model of the Human Aryl Hydrocarbon Receptor Ligand Binding Domain, Biology, vol. 399, no. 4, pp. 645 - 669, 2014.
A. Perkins, Phillips, J. Lynne, Kerkvliet, N. I., Tanguay, R., Perdew, G. H., Kolluri, S., and Bisson, W. H., A structural switch between agonist and antagonist bound conformations for a ligand-optimized model of the human aryl hydrocarbon receptor ligand binding domain, Biology, vol. 3, pp. 645–669, 2014.
Y. Zhang, Yan, T., Sun, D., Xie, C., Zheng, Y., Zhang, L., Yagai, T., Krausz, K. W., Bisson, W. H., Yang, X., and Gonzalez, F. J., Structure-activity relationships of the main bioactive constituents of Euodia ruticarpa on aryl hydrocarbon receptor activation and bile acid homeostasis, Drug Metabolism and Disposition, p. dmd.117.080176, 2018.
I. A. Murray, Flaveny, C. A., Chiaro, C. R., Sharma, A. K., Tanos, R. S., Schroeder, J. C., Amin, S. G., Bisson, W. H., Kolluri, S., and Perdew, G. H., Suppression of cytokine-mediated complement factor gene expression through selective activation of the Ah receptor with 3′, 4′-dimethoxy-$\alpha$-naphthoflavone, Molecular pharmacology, vol. 79, pp. 508–519, 2011.
L. Mu, Drandarov, K., Bisson, W. H., Schibig, A., Wirz, C., P Schubiger, A., and Westera, G., Synthesis and binding studies of epibatidine analogues as ligands for the nicotinic acetylcholine receptors, European journal of medicinal chemistry, vol. 41, pp. 640–650, 2006.

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