College of Agricultural Sciences

T. - G. Lim, Jeon, A. Ji, Yoon, J. Hye, Song, D., Kim, J. - E., Kwon, J. Yeon, Kim, J. Rhan, Kang, N. Joo, Park, J. - S., Yeom, M. Hun, Oh, D. - K., Lim, Y., Lee, C. C., Lee, C. Yong, and Lee, K. Won, “20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol, a metabolite of ginsenoside Rb1, enhances the production of hyaluronic acid through the activation of ERK and Akt mediated by Src tyrosin kinase in human keratinocytes.”, Int J Mol Med, vol. 35, no. 5, pp. 1388-94, 2015.

T. - G. Lim, Lee, B. Kyung, Kwon, J. Yeon, Jung, S. Keun, and Lee, K. Won, “Acrylamide up-regulates cyclooxygenase-2 expression through the MEK/ERK signaling pathway in mouse epidermal cells.”, Food Chem Toxicol, vol. 49, no. 6, pp. 1249-54, 2011.

S. Dagdeviren, Jung, D. Young, Lee, E., Friedline, R. H., Noh, H. Lim, Kim, J. Hun, Patel, P. R., Tsitsilianos, N., Tsitsilianos, A. V., Tran, D. A., Tsougranis, G. H., Kearns, C. C., Uong, C. P., Kwon, J. Yeon, Muller, W., Lee, K. Won, and Kim, J. K., “Altered Interleukin-10 Signaling in Skeletal Muscle Regulates Obesity-Mediated Inflammation and Insulin Resistance.”, Mol Cell Biol, vol. 36, no. 23, pp. 2956-2966, 2016.

K. Mi Lee, Kwon, J. Yeon, Lee, K. Won, and Lee, H. Joo, “Ascorbic acid 6-palmitate suppresses gap-junctional intercellular communication through phosphorylation of connexin 43 via activation of the MEK-ERK pathway.”, Mutat Res, vol. 660, no. 1-2, pp. 51-6, 2009.

W. Bum Huh, Kim, J. - E., Kang, Y. - G., Park, G., Lim, T. - G., Kwon, J. Yeon, Song, D. Som, Jeong, E. Hee, Lee, C. C., Son, J. Eun, Seo, S. Gwon, Lee, E., Kim, J. Rhan, Lee, C. Yong, Park, J. Seong, and Lee, K. Won, “Brown Pine Leaf Extract and Its Active Component Trans-Communic Acid Inhibit UVB-Induced MMP-1 Expression by Targeting PI3K.”, PLoS One, vol. 10, no. 6, p. e0128365, 2015.

S. Ho Shin, Seo, S. Gwon, Min, S., Yang, H., Lee, E., Son, J. Eun, Kwon, J. Yeon, Yue, S., Chung, M. - Y., Kim, K. - H., Cheng, J. - X., Lee, H. Joo, and Lee, K. Won, “Caffeic acid phenethyl ester, a major component of propolis, suppresses high fat diet-induced obesity through inhibiting adipogenesis at the mitotic clonal expansion stage.”, J Agric Food Chem, vol. 62, no. 19, pp. 4306-12, 2014.

H. Kang, Lee, C. Hyung, Kim, J. Rhan, Kwon, J. Yeon, Seo, S. Gwon, Han, J. Gab, Kim, B. Gon, Kim, J. - E., and Lee, K. Won, “Chlorella vulgaris Attenuates Dermatophagoides Farinae-Induced Atopic Dermatitis-Like Symptoms in NC/Nga Mice.”, Int J Mol Sci, vol. 16, no. 9, pp. 21021-34, 2015.

N. Ry Song, Yang, H., Park, J., Kwon, J. Yeon, Kang, N. Joo, Heo, Y. Seok, Lee, K. Won, and Lee, H. Joo, “Cyanidin suppresses neoplastic cell transformation by directly targeting phosphatidylinositol 3-kinase”, Food Chemistry, vol. 133, no. 3, pp. 658 - 664, 2012.

J. - E. Kim, Kwon, J. Yeon, Seo, S. Kwon, Son, J. Eun, Jung, S. Keun, Min, S. Yun, Hwang, M. Kyung, Heo, Y. - S., Lee, K. Won, and Lee, H. Joo, “Cyanidin suppresses ultraviolet B-induced COX-2 expression in epidermal cells by targeting MKK4, MEK1, and Raf-1.”, Biochem Pharmacol, vol. 79, no. 10, pp. 1473-82, 2010.

T. - G. Lim, Kwon, J. Yeon, Kim, J., Song, N. Ry, Lee, K. Mi, Heo, Y. - S., Lee, H. Joo, and Lee, K. Won, “Cyanidin-3-glucoside suppresses B[a]PDE-induced cyclooxygenase-2 expression by directly inhibiting Fyn kinase activity.”, Biochem Pharmacol, vol. 82, no. 2, pp. 167-74, 2011.

N. Joo Kang, Lee, K. Won, Kwon, J. Yeon, Hwang, M. Kyung, Rogozin, E. A., Heo, Y. - S., Bode, A. M., Lee, H. Joo, and Dong, Z., “Delphinidin attenuates neoplastic transformation in JB6 Cl41 mouse epidermal cells by blocking Raf/mitogen-activated protein kinase kinase/extracellular signal-regulated kinase signaling.”, Cancer Prev Res (Phila), vol. 1, no. 7, pp. 522-31, 2008.

J. Yeon Kwon, Lee, K. Won, Kim, J. - E., Jung, S. Keun, Kang, N. Joo, Hwang, M. Kyung, Heo, Y. - S., Bode, A. M., Dong, Z., and Lee, H. Joo, “Delphinidin suppresses ultraviolet B-induced cyclooxygenases-2 expression through inhibition of MAPKK4 and PI-3 kinase.”, Carcinogenesis, vol. 30, no. 11, pp. 1932-40, 2009.

L. Yee Cheong, Suk, S., Thimmegowda, N. R., Chung, M. - Y., Yang, H., Seo, S. Gwon, Shwetha, B., Kim, J. - E., Kwon, J. Yeon, Kim, B. Yeon, and Lee, K. Won, “Hirsutenone Directly Targets PI3K and ERK to Inhibit Adipogenesis in 3T3-L1 Preadipocytes.”, J Cell Biochem, vol. 116, no. 7, pp. 1361-70, 2015.

S. Dagdeviren, Jung, D. Young, Friedline, R. H., Noh, H. Lim, Kim, J. Hun, Patel, P. R., Tsitsilianos, N., Inashima, K., Tran, D. A., Hu, X., Loubato, M. M., Craige, S. M., Kwon, J. Yeon, Lee, K. Won, and Kim, J. K., “IL-10 prevents aging-associated inflammation and insulin resistance in skeletal muscle.”, FASEB J, vol. 31, no. 2, pp. 701-710, 2017.

N. Joo Kang, Lee, K. Mi, Kim, J. Hun, Lee, B. Kyung, Kwon, J. Yeon, Lee, K. Won, and Lee, H. Joo, “Inhibition of gap junctional intercellular communication by the green tea polyphenol (-)-epigallocatechin gallate in normal rat liver epithelial cells.”, J Agric Food Chem, vol. 56, no. 21, pp. 10422-7, 2008.

J. Yeon Kwon, Seo, S. Gwon, Yue, S., Cheng, J. - X., Lee, K. Won, and Kim, K. - H., “An inhibitory effect of resveratrol in the mitotic clonal expansion and insulin signaling pathway in the early phase of adipogenesis.”, Nutr Res, vol. 32, no. 8, pp. 607-16, 2012.

S. Gwon Seo, Yang, H., Shin, S. Ho, Min, S., Kim, Y. A., Yu, J. Gak, Lee, D. Eun, Chung, M. - Y., Heo, Y. - S., Kwon, J. Yeon, Yue, S., Kim, K. Hong, Cheng, J. - X., Lee, K. Won, and Lee, H. Joo, “A metabolite of daidzein, 6,7,4'-trihydroxyisoflavone, suppresses adipogenesis in 3T3-L1 preadipocytes via ATP-competitive inhibition of PI3K.”, Mol Nutr Food Res, vol. 57, no. 8, pp. 1446-55, 2013.

J. - E. Kim, Kwon, J. Yeon, Lee, D. Eun, Kang, N. Joo, Heo, Y. - S., Lee, K. Won, and Lee, H. Joo, “MKK4 is a novel target for the inhibition of tumor necrosis factor-alpha-induced vascular endothelial growth factor expression by myricetin.”, Biochem Pharmacol, vol. 77, no. 3, pp. 412-21, 2009.

E. Roh, Kim, J. - E., Kwon, J. Yeon, Park, J. Seong, Bode, A. M., Dong, Z., and Lee, K. Won, “Molecular mechanisms of green tea polyphenols with protective effects against skin photoaging.”, Crit Rev Food Sci Nutr, vol. 57, no. 8, pp. 1631-1637, 2017.

J. Yeon Kwon, Lee, K. Won, Hur, H. Jeon, and Lee, H. Joo, “Peonidin inhibits phorbol-ester-induced COX-2 expression and transformation in JB6 P+ cells by blocking phosphorylation of ERK-1 and -2.”, Ann N Y Acad Sci, vol. 1095, pp. 513-20, 2007.

M. - S. Kim, Kwon, J. Yeon, Kang, N. Joo, Lee, K. Won, and Lee, H. Joo, “Phloretin induces apoptosis in H-Ras MCF10A human breast tumor cells through the activation of p53 via JNK and p38 mitogen-activated protein kinase signaling.”, Ann N Y Acad Sci, vol. 1171, pp. 479-83, 2009.

J. Yeon Kwon, Seo, S. Gwon, Heo, Y. - S., Yue, S., Cheng, J. - X., Lee, K. Won, and Kim, K. - H., “Piceatannol, natural polyphenolic stilbene, inhibits adipogenesis via modulation of mitotic clonal expansion and insulin receptor-dependent insulin signaling in early phase of differentiation.”, J Biol Chem, vol. 287, no. 14, pp. 11566-78, 2012.

J. Yeon Kwon, Byun, S., and Lee, K. Won, Proteomics in Understanding the Molecular Basis of Phytochemicals for Health. Chichester, UK: John Wiley & Sons, Ltd, 2015, pp. 328 - 337.

H. Kang, Lee, C. Hyung, Kim, J. Rhan, Kwon, J. Yeon, Son, M. - J., Kim, J. - E., and Lee, K. Won, “Theobroma cacao extract attenuates the development of Dermatophagoides farinae-induced atopic dermatitis-like symptoms in NC/Nga mice.”, Food Chem, vol. 216, pp. 19-26, 2017.

E. Lee, Jung, D. Young, Kim, J. Hun, Patel, P. R., Hu, X., Lee, Y., Azuma, Y., Wang, H. - F., Tsitsilianos, N., Shafiq, U., Kwon, J. Yeon, Lee, H. Joo, Lee, K. Won, and Kim, J. K., “Transient receptor potential vanilloid type-1 channel regulates diet-induced obesity, insulin resistance, and leptin resistance.”, FASEB J, vol. 29, no. 8, pp. 3182-92, 2015.