Credits: 
3
Term: 
Spring

Course Description

Mathematical and experimental tecniques for quantitative descriptions of microbial bioreaction processes and an introduction to the principles and methodologies of metabolic engineering.  Pre-requisites:  Differential equations, linear algebra, biochemistry.

Course Objectives

The student, upon completion of this course, should be able to:

  • Perform microbial (eukaryotic/prokaryotic) stoichiometric balances.
  • Check consistency of data derived from microbial processes
  • Develop metabolic network models.
  • Perform flux balance analysis using network models.
  • Perform sensitivity analysis of simple linear pathways
  • Develop metabolic engineering case studies.

Topics

  • Blackbox Models
  • Consistency Analysis
  • Metabolic Flux Analysis
  • Flux Balance Analysis